Myxobacteria: Ubiquitous and sophisticated predatory microbes and their specialized metabolism enabling molecular interactions

Digitaler Vortrag

The discovery and development of antibiotics represents one of the most groundbreaking achievements of modern medicine. Unfortunately, the rise of antimicrobial resistance often renders these important substances ineffective, thus necessitating the search for novel antibiotics. One of the most promising sources of novel antimicrobials are microorganisms themselves. Especially soil-dwelling myxobacteria have been shown to be prolific producers of a wide range of structurally diverse bioactive compounds. In this talk, I will present our approaches to identify novel chemistry from myxobacteria and show selected examples of compounds which are currently under development in our laboratory.

Rolf Müller studied pharmacy at the University of Bonn, where he also completed his PhD in 1994. From 1996 to 1997 he was a postdoctoral fellow at the University of Washington (Seattle), then junior group leader at the Gesellschaft für Biotechnologische Forschung in Braunschweig (now Helmholtz Centre for Infection Research). He has been Professor of Pharmaceutical Biotechnology at Saarland University since 2003 and founding Director of the Helmholtz Institute for Pharmaceutical Research Saarland since 2009. He was appointed to the National Academy of Sciences Leopoldina in 2016 and received the BioFuture Prize of the BMBF in 2003 and the Leibniz Prize of the German Research Foundation in 2021.

Moderation: Professorin Dr. Ulla Bonas

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